Targeted therapeutic approach for an anaplastic thyroid cancerinvitroandinvivo
نویسندگان
چکیده
منابع مشابه
Anaplastic Thyroid Carcinoma: A Therapeutic Dilemma
Anaplastic thyroid carcinoma (ATC) is one of the most malignant human neoplasms and has a grave prognosis. This study gives an update on our experience with this unusual neoplasm, with specific focus on the response to various treatment modalities. Forty-seven patients with histologically proven ATCs were enrolled (19 men, 28 women; mean age, 62.8 years). This number represents 1.5% among a tot...
متن کاملMultimodal approach to anaplastic thyroid cancer.
Despite more than 50 years of research, the overall clinical outcomes of patients afflicted with anaplastic thyroid cancer remain dismal. Survival is limited by the dire consequences of an uncontrolled primary and the prevalence of overt or occult distant metastasis. Local control is influenced by multiple confounding variables, including the inherent biological aggressiveness of the disease an...
متن کاملprecision medicine approach to anaplastic thyroid cancer: advances in targeted drug therapy based on specific signaling pathways
personalized medicine is a set of diagnostic, prognostic and therapeutic approaches in which medical interventions are carried out based on individual patient characteristics. as life expectancy increases in developed and developing countries, the incidence of diseases such as cancer goes up among people in the community. cancer is a disease that the response to treatment varies from one person...
متن کاملMicroRNA Targeted Therapeutic Approach for Pancreatic Cancer
Pancreatic cancer remains the fourth leading cause of cancer-related death in the US and is expected to be the second leading cause of cancer-related death by 2030. Therefore, it is important to better understand the molecular pathogenesis, phenotypes and features of pancreatic cancer in order to design novel molecularly targeted therapies for achieving better therapeutic outcome of patients wi...
متن کاملLenvatinib for Anaplastic Thyroid Cancer
BACKGROUND Lenvatinib has been approved by regulatory agencies in Japan, the United States, and the European Union for treatment of radioiodine-refractory differentiated thyroid cancer (RR-DTC). Thyroid cancer, however, is a clinically diverse disease that includes anaplastic thyroid cancer (ATC), the subtype associated with the highest lethality. Effective therapy for ATC is an unmet need. P...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer Science
سال: 2008
ISSN: 1347-9032,1349-7006
DOI: 10.1111/j.1349-7006.2008.00882.x